1-naphthol (1N) is a metabolite of carbaryl and naphthalene that is an intermediate in Metabolism of xenobiotics by cytochrome P450. It is generated by spontaneous reaction from (1R,2S)-Naphthalene epoxide then is it converted to 1,4-Dihydroxynaphthalene. Although 1-Naphthol is not persistent in the body, a single urine sample may adequately predict exposure over several months to chlorpyrifos, which is a broad-spectrum organophosphate insecticide. In adult men, TCPY and 1N were associated with reduced testosterone levels (A3198, A3199).
Solubility In water, 866 mg/L at 25 °C
Formula
C10H8O
Mol. Weight
144.17
CAS #
90-15-3
Form
Powder
State
Pellets or Large Crystals
See origin →
Functions
Hair Dyeing
Reduces Inflammation
Colors Hair
Traditional Use
A synthetic compound developed in the 19th century for use as a dye intermediate and disinfectant. Later adopted in the cosmetics industry for hair coloring applications.