2-Amino-3-Hydroxypyridine
AKA “16867-03-1, 2-Amino-3-pyridinol, 3-Pyridinol, 2-amino-, 3-Hydroxy-2-pyridinamine, 3-HYDROXY-2-AMINOPYRIDINE, 2-amino, P8740PEW4B, JAROCOL 2A3HP, RODOL 2A3PYR”
Ingredient
Ingredient Facts
2-Amino-3-Hydroxypyridine
AKA: 16867-03-1, 2-Amino-3-pyridinol, 3-Pyridinol, 3-Hydroxy-2-pyridinamine, 3-HYDROXY-2-AMINOPYRIDINE, P8740PEW4B, JAROCOL 2A3HP, RODOL 2A3PYR
Ingredient · Hair Dyeing · EWG: 4
Synthetic
Not Clean
2-amino-3-hydroxypyridine is a monohydroxypyridine and an aminopyridine.
Formula
C5H6N2O
Mol. Weight
110.11
CAS #
16867-03-1
Form
Powder
See origin →
Functions
Hair Dyeing
Antioxidant Protection
Colors Hair
Traditional Use
A synthetic heterocyclic compound developed as a hair dye intermediate in the 20th century. It was created to expand the color palette available in oxidative hair coloring systems.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
2-Amino-4-nitrophenol.
IARC monographs on the evaluation of carcinogenic risks to humans, 1993
2-Amino-5-nitrophenol.
IARC monographs on the evaluation of carcinogenic risks to humans, 1993
Safety Assessment of 2-Amino-3-Hydroxypyridine as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2020
Final Report on the Safety Assessment of 2-Amino-6-Chloro-4-Nitrophenol and 2-Amino-6-Chloro-4-Nitrophenol Hydrochloride
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol and 4-Chloro-2-Aminophenol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report: Amended Safety Assessment of 4-Chloro-2-Aminophenol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of 2-Amino-3-Hydroxypyridine as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of 2-Amino-4-Hydroxyethylaminoanisole and 2-Amino-4-Hydroxyethylaminoanisole Sulfate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
2-Amino-3-Hydroxypyridine
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Amino-4-Hydroxyethylaminoanisole
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Amino-4-Hydroxyethylaminoanisole Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Amino-6-Chloro-4-Nitrophenol
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Amino-3-Hydroxypyridine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Amino-4-Hydroxyethylaminoanisole
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Amino-4-Hydroxyethylaminoanisole Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Amino-5-Nitrophenol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Amino-6-Chloro-4-Nitrophenol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Amino-1,2-bis(4-methoxyphenol) ethanol and its salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
2-Amino-4-nitrophenol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
2-Amino-5-nitrophenol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
2-Amino-4-hydroxyethylaminoanisole sulfate - a coupler causing contact allergy from use in hair dyes.
Madsen JT, Andersen KE
Contact dermatitis, 2016
2-Amino-4-hydroxyethylaminoanisole sulfate - a coupler causing contact allergy from use in hair dyes.
Madsen JT, Andersen KE
Contact dermatitis, 2016
Dietary ceramide 2-aminoethylphosphonate, a marine sphingophosphonolipid, improves skin barrier function in hairless mice.
Tomonaga N, Manabe Y, Aida K, Sugawara T
Scientific reports, 2020
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR