2-Oleamido-1,3-Octadecanediol
AKA “54422-45-6, 30D478BUNR, MEXANYL GZ, 9-Octadecenamide, N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, (9Z)-, N-[2-hydroxy-1-(hydroxymethyl)heptadecyl]-, RefChem:549537, 2-OLEAMIDO-1, 3-OCTADECANEDIOL [INCI], 416-630-8, (Z)-N-(1, 3-dihydroxyoctadecan-2-yl)octadec-9-enamide
Skin Conditioning
Ingredient Facts
2-Oleamido-1,3-Octadecanediol
AKA: 54422-45-6, 30D478BUNR, MEXANYL GZ, 9-Octadecenamide, N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, (9Z)-, N-[2-hydroxy-1-(hydroxymethyl)heptadecyl]-, RefChem:549537, 3-OCTADECANEDIOL [INCI], 416-630-8, (Z)-N-(1, 3-dihydroxyoctadecan-2-yl)octadec-9-enamide
Skin Conditioning · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Clean
2-(9-(Z)-Octadecenylamido)-1,3-octadecanediol
Formula
C36H71NO3
Mol. Weight
566.00
CAS #
54422-45-6
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic emulsifier and conditioning agent developed in the late 20th century. Derived from oleic acid (found in olive oil and other plant oils) and engineered for cosmetic formulations.
Skin Types
all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR