4-Chlororesorcinol
AKA “95-88-5, 4-chlorobenzene-1, 3-diol, 4-Chlororesorcin, p-Chlororesorcinol, 1, 3-Benzenediol, 4-chloro-, 4-Chloro-1, 3-benzenediol, 6-Chlororesorcinol, Resorcinol, 3-dihydroxybenzene”
Ingredient
Ingredient Facts
4-Chlororesorcinol
AKA: 95-88-5, 4-chlorobenzene-1, 3-diol, P-Chlororesorcinol, 1, 3-Benzenediol, 4-chloro-, 4-Chloro-1, 3-benzenediol, 6-Chlororesorcinol, 3-dihydroxybenzene
Ingredient · Hair Dyeing · EWG: 6
Synthetic
Safety Concern
Not Clean
1,3-Benzenediol, 4-chloro-
Formula
C6H5ClO2
Mol. Weight
144.55
CAS #
95-88-5
Form
Powder
State
Beige-brown solid; [EC: SCCS - Opinion] Light beige granular powder with a mild phenolic odor; [Jos. H. Lowenstein and Sons MSDS]
See origin →
Functions
Hair Dyeing
Colors Hair
Traditional Use
A synthetic derivative of resorcinol with halogenation for enhanced chemical stability. Developed in the 20th century for use as a hair dye coupler in permanent color systems.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
EWG
6
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
ewg-6
medical-approval
all-shades-safe
Phototoxicity Concern
Concentration Guide
5%
0%7%
Reg. Limit
EU regulatory limit: 5%. 0,. (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 1... Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 22.
Regulatory Agencies
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
4-Chlororesorcinol.
Burnett CL
International journal of toxicology, 2017
Addendum to the Final Report on the Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol (JEPT 4(4) 47-61 1980)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report of the Safety Assessment for 2-Bromo-2-Nitropropane-1,3-Diol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of 2-Methylresorcinol and Resorcinol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of 4-Chlororesorcinol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol and 4-Chloro-2-Aminophenol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report: Amended Safety Assessment of 4-Chloro-2-Aminophenol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report: Amended Safety Assessment of 5-Amino-4-Chloro-o-Cresol and 5-Amino-4-Chloro-o-Cresol HCl as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Revised Tentative Report: Amended Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
2-Bromo-2-Nitropropane-1,3-Diol
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Methylresorcinol
European Commission
EU Cosmetic Ingredient Database (CosIng)
4-Chlororesorcinol
European Commission
EU Cosmetic Ingredient Database (CosIng)
5-Amino-4-Chloro-o-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
5-Amino-4-Chloro-o-Cresol HCl
European Commission
EU Cosmetic Ingredient Database (CosIng)
Resorcinol
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Bromo-2-Nitropropane-1,3-Diol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Methylresorcinol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
4-Chlororesorcinol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Resorcinol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Bromo-2-nitropropane-1,3-diol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Resorcinol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Kitty Litter Dermatitis from-Bromo-2-Nitropropane-1,3-Diol.
Sullenbarger JW, Hensley B, Travers JB
Skinmed, 2017
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR