5-Bromo-5-Nitro-1,3-Dioxane
AKA “Bronidox, 3-Dioxane, 5-Bromo-5-nitro-m-dioxane, m-DIOXANE, MICROCIDE I”
Synthetic
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Ingredient Facts
5-Bromo-5-Nitro-1,3-Dioxane
AKA: Bronidox, 5-Bromo-5-nitro-m-dioxane, M-DIOXANE, MICROCIDE I
Synthetic · Preservative | Antimicrobial · EWG: 4
Plant-Derived
Preservative
Synthetic
Clean
A preservative that keeps formulas fresh and prevents bacterial growth, helping your product stay safe and effective from first use to last.
Formula
C4H6BrNO4
Mol. Weight
212.00
CAS #
30007-47-7
Form
Powder
Plant-Derived
Synthetic. Synthesized from 1,3-dioxane, a six-membered cyclic ether compound, through organic chemistry reactions. Produced by introducing bromine and nitro functional groups onto the dioxane ring structure.
Function
Preservative | Antimicrobial
Benefits
Preserves Formula
Prevents microbial growth
Traditional Use
Synthetic preservative developed in the late 20th century for use in cosmetic and personal care products. Created to provide broad-spectrum antimicrobial protection in formulations.
Skin Types
all-skin-types
Best For
Target
General
Melanin-Rich Skin
Suitable
Pregnancy Safe
Caution
EWG Score4
CIR Safety Findings
medical-approval, all-shades-safe
Concentration Guide
0.1%
0%0%
Reg. Limit
EU regulatory limit: 0.1%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex V (Preservatives), Entry 20.
Regulatory Agencies
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR