Acetamide MEA
AKA “N-(2-Hydroxyethyl)acetamide, N-Acetylethanolamine, 142-26-7, 2-Acetamidoethanol, Acetylcolamine, Acetamide, N-(2-hydroxyethyl)-, 2-Acetylaminoethanol, N-Ethanolacetamide, N-Acetyl-2-aminoethanol
Surfactant
Ingredient Facts
Acetamide mea
AKA: N-(2-Hydroxyethyl)acetamide, N-Acetylethanolamine, 142-26-7, 2-Acetamidoethanol, Acetylcolamine, N-(2-hydroxyethyl)-, 2-Acetylaminoethanol, N-Ethanolacetamide, N-Acetyl-2-aminoethanol
Surfactant · Humectant · EWG: 4
Synthetic
Humectant
Cleanser
Skin Conditioner
Hair Care
Not Clean
The CIR Expert Panel concluded that the ethanolamides listed subsequently are safe in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating. The Expert Panel cautioned that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Acetamide MEA
Solubility SOL IN ALL PROP IN WATER; SOL IN HOT ACETONE; SLIGHTLY SOL IN BENZENE, PETROLEUM ETHER
Formula
C4H9NO2
Mol. Weight
103.12
CAS #
142-26-7
Form
Liquid
State
Liquid
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Viscosity Controlling
Locks In Moisture
Traditional Use
Developed as a synthetic humectant in the early 20th century to provide moisture retention in cosmetic formulations, replacing some traditional plant-derived glycerols.
Skin Types
all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
ewg-4
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Final Report on the Safety Assessment of Acetamide MEA
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Chloroacetamide
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Acetamide MEA
European Commission
EU Cosmetic Ingredient Database (CosIng)
Chloroacetamide
European Commission
EU Cosmetic Ingredient Database (CosIng)
Acetamide MEA
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-(4-Allyl-2-methoxyphenoxy)-N,N-diethylacetamide and its salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Chloroacetamide
Health Canada
Health Canada Cosmetic Ingredient Hotlist
N-5-Chlorobenzoxazol-2-ylacetamide and its salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Chloroacetamide derivatives as a promising topical treatment for fungal skin infections.
Machado GDRM, Fernandes de Andrade S, Pippi B, Bergamo VZ, Jacobus Berlitz S et al.
Mycologia, 2019
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR