Acetyl Glutamine
AKA “Aceglutamide, 2490-97-3, L-Glutamine, N2-acetyl-, N2-Acetyl-L-glutamine, Aceglutamida, Aceglutamidum, Glutamine, L-, NEURAMINA, DTXSID2048959”
Skin Conditioning
Ingredient Facts
Acetyl glutamine
AKA: Aceglutamide, 2490-97-3, L-Glutamine, N2-acetyl-, N2-Acetyl-L-glutamine, Aceglutamida, Aceglutamidum, L-, NEURAMINA, DTXSID2048959
Skin Conditioning · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Amino Acid
Clean
N-acetyl-L-glutamine is an N2-acetylglutamine that has L-configuration. It has a role as a human metabolite. It is a N(2)-acyl-L-glutamine, a N-acetyl-L-amino acid and a N(2)-acetylglutamine. It is a conjugate acid of a N-acetyl-L-glutaminate. It is an enantiomer of a N(2)-acetyl-D-glutamine.
Formula
C7H12N2O4
Mol. Weight
188.18
CAS #
2490-97-3
Form
Liquid
State
Solid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic derivative of the amino acid glutamine developed for use in skincare to improve skin hydration and support cellular regeneration.
Skin Types
●all-skin-types, gentle
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Acetyl Glutamine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glutamine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis.
Eelen G, Dubois C, Cantelmo AR, Goveia J, Brüning U et al.
Nature, 2018
Acetyl Glutamine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR