Adenosine
AKA “58-61-7, Adenocard, Adenoscan, Adenine riboside, Nucleocardyl, beta-D-Adenosine, Boniton, Sandesin, Myocol
Synthetic
Ingredient Facts
Adenosine
AKA: 58-61-7, Adenocard, Adenoscan, Adenine riboside, Nucleocardyl, Beta-D-Adenosine, Boniton, Sandesin, Myocol
Synthetic · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Synthetic
Clean
Adenosine is a nucleoside that is composed of adenine and d-ribose. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. For instance, adenosine plays an important role in energy transfer - as adenosine triphosphate (ATP) and adenosine diphosphate (ADP). It also plays a role in signal transduction as cyclic adenosine monophosphate, cAMP. Adenosine itself is both a neurotransmitter and potent vasodilator. When administered intravenously, adenosine causes transient heart block in the AV node. Because of the effects of adenosine on AV node-dependent supraventricular tachycardia, adenosine is considered a class V antiarrhythmic agent.
Solubility Water solubility increases by warming and lowering the pH
Formula
C10H13N5O4
Mol. Weight
267.24
CAS #
58-61-7
State
Solid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Skin
Softens & Smooths
Traditional Use
This is a CAS number (for creatinine) without an INCI name, making historical context difficult to assign. If this refers to the amino acid derivative, it has no traditional cosmetic use but may be used in modern skincare formulations.
EWG
1
CIR
Insufficient
Pregnancy
CIR Safety Findings
all-shades-safe
Phototoxicity Concern
Regulatory Status
USAunder review
CANADApermitted
Regulatory Agencies
Safety Assessment of Adenosine as Used in Cosmetics.
Cherian P, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2024
Safety Assessment of Adenosine as Used in Cosmetics.
Cherian P, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2024
Safety Assessment of Adenosine as Used in Cosmetics.
Cherian P, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2024
Safety Assessment of Adenosine as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Adenosine Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adenosine Triphosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Disodium Adenosine Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Disodium Adenosine Triphosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adenosine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Adenosine Phosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Adenosine Triphosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Disodium Adenosine Triphosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR