Aminomethylpropanediol
AKA “Aminomethyl Propanediol
Ingredient
Ingredient Facts
Aminomethylpropanediol
AKA: Aminomethyl Propanediol
Ingredient · Humectant · EWG: 4
Plant-Derived Synthetic
Humectant
Solvent
Not Clean
Aminomethylpropanediol is a cosmetic ingredient. Assessed as safe by the CIR.
CAS #
2163-42-0
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Dissolves Ingredients
Dissolves other ingredients
Traditional Use
Developed in the mid-20th century as a synthetic pH buffer and preservative booster for cosmetics and personal care products. Used to neutralize acids and stabilize formulations rather than derived from traditional sources.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Safety Assessment of Tromethamine, Aminomethyl Propanediol, and Aminoethyl Propanediol as Used in Cosmetics.
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2018
Safety Assessment of Tromethamine, Aminomethyl Propanediol, and Aminoethyl Propanediol as Used in Cosmetics.
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2018
Final amended report on safety assessment on aminomethyl propanol and aminomethyl propanediol.
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final Amended Report on the Safety Assessment of Aminomethyl Propanol and Aminomethyl Propanediol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Aminomethylpropanol and Aminomethylpropanediol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Tromethamine, Aminomethyl Propanediol and Aminoethyl Propanediol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Aminomethyl Propanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Jun 2026
Data: CosIng · EWG · CIR