Ascorbyl Dipalmitate
AKA “L-Ascorbic acid, dihexadecanoate, UNII-624RX3IESR, RefChem:201398, 28474-90-0, [(2R)-2-[(1S)-1-hexadecanoyloxy-2-hydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-yl] hexadecanoate, SCHEMBL285548, TZMXUZAZMXYWGC-LBHUVFDKSA-N, MSK160929, NS00013371, (2R)-2-[(1S)-1-(Hexadecanoyloxy)-2-hydroxyethyl]-4-hydroxy-5-oxo-2, 5-dihydrofuran-3-yl hexadecanoate
Antioxidant
Ingredient Facts
Ascorbyl dipalmitate
AKA: L-Ascorbic acid, Dihexadecanoate, UNII-624RX3IESR, RefChem:201398, 28474-90-0, [(2R)-2-[(1S)-1-hexadecanoyloxy-2-hydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-yl] hexadecanoate, SCHEMBL285548, TZMXUZAZMXYWGC-LBHUVFDKSA-N, MSK160929, NS00013371, (2R)-2-[(1S)-1-(Hexadecanoyloxy)-2-hydroxyethyl]-4-hydroxy-5-oxo-2, 5-dihydrofuran-3-yl hexadecanoate
Antioxidant · Antioxidant · EWG: 1
Synthetic
Antioxidant
Vitamin C
Clean
L-Ascorbic acid, dihexadecanoate
Formula
C38H68O8
Mol. Weight
652.90
CAS #
28474-90-0
Form
Liquid
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Neutralizes Free Radicals
Traditional Use
Developed in the mid-20th century as a fat-soluble derivative of vitamin C to improve stability and skin penetration compared to L-ascorbic acid, addressing the instability issues of native vitamin C in skincare.
Skin Types
all-skin-types, gentle
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Phototoxicity Concern
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Final Report on the Safety Assessment of Ascorbyl Palmitate, Ascorbyl Dipalmitate, Ascorbyl Stearate, Erythorbic Acid, and Sodium Erythorbate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Ascorbyl Dipalmitate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
Ascorbyl Dipalmitate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2001
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR