Brucine
AKA “Brucine sulfate, Brucine sulphate, 4845-99-2, KY7O12XPOQ, Brucine sulfate anhydrous, Brucine sulphate anhydrous, NSC-463, Strychnidin-10-one, 2, 3-dimethoxy-, sulfate (2:1), 10, 11-DIMETHOXYSTRYCHNINE SULFATE, RefChem:1080193
Ingredient
Ingredient Facts
Brucine
AKA: Brucine sulfate, Brucine sulphate, 4845-99-2, KY7O12XPOQ, Brucine sulfate anhydrous, Brucine sulphate anhydrous, NSC-463, Strychnidin-10-one, 2, 3-dimethoxy-, Sulfate (2:1), 10, 11-DIMETHOXYSTRYCHNINE SULFATE, RefChem:1080193
Ingredient · Denaturant · EWG: 5
Synthetic
Not Clean
2,3-Dimethoxystrychnidin-10-one Sulfate (2:1)
Formula
C46H54N4O12S
Mol. Weight
887.00
CAS #
4845-99-2
Form
Liquid
State
Off-white powder; [Sigma-Aldrich MSDS]
See origin →
Functions
Denaturant
Makes Alcohol Undrinkable
Reduces Inflammation
Locks In Moisture
Traditional Use
An alkaloid compound extracted from the Strychnos nux-vomica tree, traditionally used in Chinese and Ayurvedic medicine for pain relief and inflammation. Its use in modern cosmetics is minimal and primarily historical.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
EWG
5
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR