Brucine Sulfate
AKA “
Brucine sulphate, 4845-99-2, KY7O12XPOQ, Brucine sulfate anhydrous, Brucine sulphate anhydrous, NSC-463, Strychnidin-10-one, 2, 3-dimethoxy-, sulfate (2:1), 10, 11-DIMETHOXYSTRYCHNINE SULFATE, RefChem:1080193
”
Ingredient
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❤️
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Ingredient Facts
Brucine sulfate
AKA: Brucine sulphate, 4845-99-2, KY7O12XPOQ, Brucine sulfate anhydrous, Brucine sulphate anhydrous, NSC-463, Strychnidin-10-one, 2, 3-dimethoxy-, Sulfate (2:1), 10, 11-DIMETHOXYSTRYCHNINE SULFATE, RefChem:1080193
Ingredient · Denaturant · EWG: 2
WHAT IS IT?
Synthetic
Clean
2,3-Dimethoxystrychnidin-10-one Sulfate (2:1)
Formula
C46H54N4O12S
Mol. Weight
887.00
CAS #
4845-99-2
Form
Powder
State
Off-white powder; [Sigma-Aldrich MSDS]
See origin →
WHAT'S IT DO?
Functions
Denaturant
Makes Alcohol Undrinkable
Fights Bacteria
Antioxidant Protection
Reduces Inflammation
Traditional Use
A salt form of the plant alkaloid brucine developed for medicinal applications rather than cosmetics. It has no significant traditional cosmetic use history.
Skin Types
●
all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
No
IS IT SAFE?
EWG
2
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not a Sensitizer
ewg-2
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USA
✔ permitted
EU
✔ permitted
JAPAN
✔ permitted
CANADA
✔ permitted
Regulatory Agencies
EWG
CIR
FDA
EU COSING
Health Canada
WHAT'S THE PROOF?
Brucine Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Brucine Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
