Buteth-3
AKA “TRIETHYLENE GLYCOL MONOBUTYL ETHER, Butoxytriglycol, Butyltriglycol, Ethanol, 2-(2-(2-Butoxyethoxy)ethoxy)ethanol, HSDB 5645, EINECS 205-592-6, UNII-OC116GRO69
Synthetic
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Ingredient Facts
Buteth-3
AKA: TRIETHYLENE GLYCOL MONOBUTYL ETHER, Butoxytriglycol, Butyltriglycol, Ethanol, 2-(2-(2-Butoxyethoxy)ethoxy)ethanol, HSDB 5645, EINECS 205-592-6, UNII-OC116GRO69
Synthetic · Solvent | Skin Conditioning | Emollient | Humectant · EWG: 4
Plant-Derived
Humectant
Emollient
Solvent
Skin Conditioner
Synthetic
Clean
A gentle solvent that helps dissolve and blend other ingredients together, ensuring your product has a smooth, consistent texture.
Solubility Very soluble in ethanol, methanol
Formula
C10H22O4
Mol. Weight
206.28
CAS #
143-22-6
Form
Liquid
Plant-Derived
Synthetic. Derived from ethylene oxide and butanol, both petrochemical-based compounds from crude oil refining. Synthesized through ethoxylation, where ethylene oxide is chemically bonded to butanol in a catalytic reaction.
Function
Solvent | Skin Conditioning | Emollient | Humectant
Benefits
Dissolves Ingredients
Dissolves other ingredients
Traditional Use
A synthetic emulsifier and surfactant derived from petrochemicals, developed in the mid-20th century for use in cosmetic and personal care formulations. No traditional use history.
Skin Types
all-skin-types
Best For
Target
General
Melanin-Rich Skin
Suitable
Pregnancy Safe
Yes
EWG Score4
CIR Safety Findings
medical-approval, all-shades-safe, Not a Sensitizer
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Safety review of phenoxyethanol when used as a preservati...
B Dréno, T Zuberbier, C Gelmetti, G Gontijo, M Marinovich
Journal of the European Academy of Dermatology and Venereology : JEADV, 2019
Safety Assessment of Diethanolamine and Its Salts as Used...
Monice M Fiume, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen + 6 more
International journal of toxicology, 2017
Safety Assessment of Diethanolamine and Its Salts as Used...
Monice M Fiume, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen + 6 more
International journal of toxicology, 2017
Safety Assessment of Diethanolamine and Its Salts as Used...
Monice M Fiume, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen + 6 more
International journal of toxicology, 2017
Phenoxyethanol Safety Assessment
Cosmetic Ingredient Review Expert Panel
International Journal of Toxicology, 2019
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR