undefined 1
undefined 2
undefined 3
undefined 4
Calcium Salicylate
AKA “Calcium disalicylate, 824-35-1, Benzoic acid, 2-hydroxy-, calcium salt (2:1), 0841QCS0DK, DTXSID60890489, RefChem:573557, DTXCID501029737, 212-525-4”
Preservative
Ingredient Facts
Calcium salicylate
AKA: Calcium disalicylate, 824-35-1, Benzoic acid, 2-hydroxy-, Calcium salt (2:1), 0841QCS0DK, DTXSID60890489, RefChem:573557, DTXCID501029737, 212-525-4
Preservative · Preservative · EWG: 4
Synthetic
Preservative
Chemical Exfoliant
Not Clean
The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Calcium Salicylate...
Formula
C14H10CaO6
Mol. Weight
314.30
CAS #
824-35-1
Form
Powder
State
White crystalline solid; [Chem Service MSDS]
See origin →
Functions
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Preserves Formula
Fights Bacteria
Reduces Inflammation
Prevents microbial growth
Traditional Use
Salicylic acid derivatives were studied in the 20th century for their exfoliating properties. The calcium salt form was developed as a milder alternative to free salicylic acid in skincare products.
Skin Types
●all-skin-types
Best For
Acne
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not Phototoxic
medical-approval
all-shades-safe
Concentration Guide
0.5%
0%1%
Reg. Limit
EU regulatory limit: 0.5%. Not to be used for children under 3 years of age (2) Source: EU Cosmetics Regulation (EC) 1223/2009, Annex V (Preservatives), Entry 3.
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Benzyl Alcohol, Benzoic Acid, Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Iso
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.
Corral-Sarasa J, Martínez-Gálvez JM, González-García P, Wendling O, Jiménez-Sánchez L et al.
Cell reports, 2024
→
4-Hydroxybenzoic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Calcium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
4-Hydroxybenzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Benzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR