Caprylhydroxamic Acid
AKA “OCTANOHYDROXAMIC ACID, N-Hydroxyoctanamide, 7377-03-9, Caprylohydroxamic acid, Octanamide, N-hydroxy-, Octanoylhydroxamic acid, UPY805K99W, DTXSID8074609, RefChem:167792”
Synthetic
Ingredient Facts
Caprylhydroxamic acid
AKA: OCTANOHYDROXAMIC ACID, N-Hydroxyoctanamide, 7377-03-9, Caprylohydroxamic acid, Octanamide, N-hydroxy-, Octanoylhydroxamic acid, UPY805K99W, DTXSID8074609, RefChem:167792
Synthetic · Buffering · EWG: 4
Synthetic
Skin Conditioner
Plant Oil
Synthetic
Not Clean
used as ruminal urease inhibitor; structure; RN given refers to unlabeled parent cpd
Formula
C8H17NO2
Mol. Weight
159.23
CAS #
7377-03-9
Form
Liquid
State
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Buffering
Removes Metal Ions
Binds metal ions
Traditional Use
A modern synthetic preservative and antimicrobial agent developed as part of cosmetic preservation science research. Created to provide broad-spectrum antimicrobial protection in formulations as an alternative to traditional preservatives.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
An epidemic of allergic contact dermatitis caused by a new allergen, caprylhydroxamic acid, in moisturizers.
Ackermann L, Virtanen H, Korhonen L, Laukkanen A, Huilaja L et al.
Contact dermatitis, 2017
An epidemic of allergic contact dermatitis caused by a new allergen, caprylhydroxamic acid, in moisturizers.
Ackermann L, Virtanen H, Korhonen L, Laukkanen A, Huilaja L et al.
Contact dermatitis, 2017
Safety Assessment of Caprylhydroxamic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Caprylohydroxamic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR