Ceramide 1
AKA “Ceramide 1 [INCI], Stearoyloxyheptacosanoyl-4-hydroxysphinganine, Stearoyloxyheptacosanoyl-C18-phytosphingosine, 4-Octadecanetriol, 2-stearoyloxyheptacosamide, CERAMIDE 1 (RETIRED)
Skin Conditioning
Ingredient Facts
Ceramide 1
AKA: Ceramide 1 [INCI], Stearoyloxyheptacosanoyl-4-hydroxysphinganine, Stearoyloxyheptacosanoyl-C18-phytosphingosine, 4-Octadecanetriol, 2-stearoyloxyheptacosamide, CERAMIDE 1 (RETIRED)
Skin Conditioning · Hair Conditioning · EWG: 4
Synthetic
Skin Conditioner
Hair Care
Ceramide
Not Clean
Ceramide 1 (Retired) is the N-acylated phytosphingosine having the erythro structure that conforms generally to the formula, where n has a value ranging from 10 to 20.The INCI Name, Ceramide 1, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 1 will be retained in the retired monograph, and also published with the new name assignment, Ceramide EOP.
Formula
C63H125NO6
Mol. Weight
992.7
CAS #
100403-19-8
Form
Liquid
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
Identified in the 1980s as a key component of skin's natural lipid barrier. Synthetic ceramides were developed to replicate skin's own ceramide structure and restore barrier function in modern skincare.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR