Ceramide 6 II
AKA “Ceramide AP, ceramide 6, Ceramide VI, Cytomide VI, Biomide 6
Skin Conditioning
Ingredient Facts
Ceramide 6 ii
AKA: Ceramide AP, Ceramide VI, Cytomide VI, Biomide 6
Skin Conditioning · Hair Conditioning · EWG: 4
Synthetic
Skin Conditioner
Hair Care
Ceramide
Not Clean
Ceramide 6 II (Retired) is the N-acylated phytosphingosine having the erythro structure that conforms generally to the formula, where m has a value ranging from 13 to 27 and n has a value ranging from 12 to 20.The INCI Name, Ceramide 6 II, originally developed in 1997, was designated with a retired status in 2014. For an interim period of time, trade name assignments formerly published with the INCI Name Ceramide 6 II will be retained in the retired monograph, and also published with the new nam
Formula
C36H73NO5
Mol. Weight
600.0
CAS #
100403-19-8
Form
Liquid
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
A specific ceramide subtype identified through advanced skin lipid analysis. Synthetically produced to accurately replicate the skin's natural ceramide composition for barrier repair in modern skincare formulations.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR