Ceramide NG
AKA “Ceramide 2, n-stearoyl dihydrosphingosine, Ceramide NS, Ceramide 2 pure, C04977SRJ5, (2S, 3R)-2-(Octadecanoylamino)octadecane-1, 3-diol, 1-stearoyl-C18-sphingosine, palmitoyl-c16-dihydrosphingosine, CERAMIDE TIC-001
Synthetic
Ingredient Facts
Ceramide ng
AKA: Ceramide 2, N-stearoyl dihydrosphingosine, Ceramide NS, Ceramide 2 pure, C04977SRJ5, (2S, 3R)-2-(Octadecanoylamino)octadecane-1, 3-diol, 1-stearoyl-C18-sphingosine, Palmitoyl-c16-dihydrosphingosine, CERAMIDE TIC-001
Synthetic · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Ceramide
Synthetic
Clean
N-octodecanoylsphinganine is a dihydroceramide in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl). It has a role as a mouse metabolite. It is a N-stearoyl-sphingoid base and a N-acylsphinganine. It is functionally related to an octadecanoic acid.
Formula
C36H73NO3
Mol. Weight
568.00
CAS #
2304-80-5
Form
Liquid
State
Solid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning Miscellaneous
Improves skin feel
Traditional Use
A synthetic humectant and emollient developed for cosmetic use in the late 20th century. Created to improve hydration and skin conditioning without natural historical precedent.
Skin Types
all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Addendum to the Final Report on the Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol (JEPT 4(4) 47-61 1980)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report of the Safety Assessment for 2-Bromo-2-Nitropropane-1,3-Diol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Revised Tentative Report: Amended Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
2-Bromo-2-Nitropropane-1,3-Diol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ceramide 2
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ceramide NS
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ceramide NS Dilaurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Bromo-2-Nitropropane-1,3-Diol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Ceramide NG
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Ceramide NS
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Bromo-2-nitropropane-1,3-diol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Kitty Litter Dermatitis from-Bromo-2-Nitropropane-1,3-Diol.
Sullenbarger JW, Hensley B, Travers JB
Skinmed, 2017
Dietary ceramide 2-aminoethylphosphonate, a marine sphingophosphonolipid, improves skin barrier function in hairless mice.
Tomonaga N, Manabe Y, Aida K, Sugawara T
Scientific reports, 2020
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR