Cholecalciferol, 1 Alpha,25 Dihydroxy
AKA “Calcitriol, 25-dihydroxycholecalciferol, Active vitamin D3”
Ingredient
Ingredient Facts
Cholecalciferol, 1 alpha,25 dihydroxy
AKA: Calcitriol, 25-dihydroxycholecalciferol, Active vitamin D3
Ingredient · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Clean
Cholecalciferol, 1 Alpha,25 Dihydroxy is a cosmetic ingredient. Rated low hazard by EWG.
Formula
C27H44O3
Mol. Weight
416.64
CAS #
32222-06-3
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Antioxidant
Anti-Inflammatory
Antimicrobial
Provides scent
Traditional Use
The active metabolite of vitamin D was first identified in 1937. Its use in skincare developed in the 2000s when research demonstrated its role in skin barrier function, immune regulation, and anti-inflammatory benefits.
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR