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Citrus grandis (Grapefruit) seed oil unsaponifiables
AKA “Grapefruit Seed Oil Unsaponifiables”
Oil
Ingredient Facts
Citrus grandis (Grapefruit) seed oil unsaponifiables
AKA: Grapefruit Seed Oil Unsaponifiables
Oil · Hair Conditioning · EWG: 4
Plant-Derived
Skin Conditioner
Hair Care
Not Clean
Citrus Grandis (Grapefruit) Seed Oil Unsaponifiables is a cosmetic ingredient used as hair conditioning, skin conditioning. Assessed as safe by the CIR.
Family
Rutaceae (Citrus family)
Plant Part
Seed
Lifeform
Tree
Climate
Wet tropical
CAS #
90045-43-5 / 8016-20-4
Form
Oil
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Hair Conditioning, Skin Conditioning, Anti
Inflammatory, Moisturizing, Boosts Collagen, Softens and smooths skin, Softens and detangles hair
Traditional Use
Grapefruit seed extract gained popularity in the 1970s as a natural antimicrobial agent. Modern skincare adopted it for its high antioxidant content, though traditional use of grapefruit itself is relatively recent compared to other citrus fruits.
Skin Types
●all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Diospyros lotus leaf and grapefruit stem extract synergistically ameliorate atopic dermatitis-like skin lesion in mice by suppressing infiltration of
Cho BO, Che DN, Yin HH, Shin JY, Jang SI
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017
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Citrus Grandis (Grapefruit)
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Citrus Grandis (Grapefruit) Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Fruit Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Fruit Water
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Fruit/Peel Water
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Juice
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Leaf Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Peel
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
citrus grandis (grapefruit) peel extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Peel Oil
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Peel Powder
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Seed Oil
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit) Seed Oil Unsaponifiables
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Paradisi (Grapefruit) Fruit Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Paradisi (Grapefruit) Fruit Water
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Paradisi (Grapefruit) Juice
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Paradisi (Grapefruit) Peel Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Paradisi (Grapefruit) Peel Oil
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Paradisi (Grapefruit) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Paradisi (Grapefruit) Seed Oil
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hydrogenated Grapefruit Seed Oil
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hydrogenated Grapefruit Seed Oil Unsaponifiables
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Citrus Grandis (Grapefruit)
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Grandis (Grapefruit) Fruit Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Grandis (Grapefruit) Fruit Water
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Grandis (Grapefruit) Juice
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Grandis (Grapefruit) Leaf Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Grandis (Grapefruit) Peel
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
citrus grandis (grapefruit) peel extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Grandis (Grapefruit) Peel Oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Grandis (Grapefruit) Seed Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Grandis (Grapefruit) Seed Oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Paradisi (Grapefruit) Fruit Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Paradisi (Grapefruit) Juice
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus paradisi (grapefruit) oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Paradisi (Grapefruit) Peel Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Paradisi (Grapefruit) Peel Oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Paradisi (Grapefruit) Seed Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Citrus Paradisi (Grapefruit) Seed Oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Development and validation of an HPLC/UV/MS method for simultaneous determination of 18 preservatives in grapefruit seed extract.
Ganzera M, Aberham A, Stuppner H
Journal of agricultural and food chemistry, 2006
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Development and validation of an HPLC/UV/MS method for simultaneous determination of 18 preservatives in grapefruit seed extract.
Ganzera M, Aberham A, Stuppner H
Journal of agricultural and food chemistry, 2006
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Outgoing and potential trends of composition, health benefits, juice production and waste management of the multi-faceted Grapefruit Citrus Χ paradisi
Khalil MNA, Farghal HH, Farag MA
Critical reviews in food science and nutrition, 2022
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Outgoing and potential trends of composition, health benefits, juice production and waste management of the multi-faceted Grapefruit Citrus Χ paradisi
Khalil MNA, Farghal HH, Farag MA
Critical reviews in food science and nutrition, 2022
→
Outgoing and potential trends of composition, health benefits, juice production and waste management of the multi-faceted Grapefruit Citrus Χ paradisi
Khalil MNA, Farghal HH, Farag MA
Critical reviews in food science and nutrition, 2022
→
Outgoing and potential trends of composition, health benefits, juice production and waste management of the multi-faceted Grapefruit Citrus Χ paradisi
Khalil MNA, Farghal HH, Farag MA
Critical reviews in food science and nutrition, 2022
→
Outgoing and potential trends of composition, health benefits, juice production and waste management of the multi-faceted Grapefruit Citrus Χ paradisi
Khalil MNA, Farghal HH, Farag MA
Critical reviews in food science and nutrition, 2022
→
Development of a comprehensive analytical method for furanocoumarins in grapefruit and their metabolites in plasma and urine using UPLC-MS/MS: a preli
Lee SG, Kim K, Vance TM, Perkins C, Provatas A et al.
International journal of food sciences and nutrition, 2016
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Protective Effects of Grapefruit Essential Oil against Staphylococcus Aureus-Induced Inflammation and Cell Damage in Human Epidermal Keratinocytes.
Zhang X, Xu H, Hua J, Zhu Z, Wang M
Chemistry & biodiversity, 2022
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Verified Jun 2026
Data: Kew POWO · CosIng · EWG · CIR