Copper Gluconate
AKA “527-09-3, Copper(II) gluconate, Copper(II)gluconate, CUPRIC GLUCONATE, Copper D-gluconate (1:2), Gluconic acid, copper(2+) salt, Cupric gluconate monohydrate, Copper(2+) D-gluconate, (1:2), Bis(D-gluconato-O1, O2)copper
Synthetic
Ingredient Facts
Copper gluconate
AKA: 527-09-3, Copper(II) gluconate, Copper(II)gluconate, CUPRIC GLUCONATE, Copper D-gluconate (1:2), Gluconic acid, Copper(2+) salt, Cupric gluconate monohydrate, Copper(2+) D-gluconate, (1:2), Bis(D-gluconato-O1, O2)copper
Synthetic · Chelating · EWG: 2
Synthetic
Chelating Agent
Synthetic
Clean
Copper Gluconate is the orally bioavailable copper salt of D-gluconic acid. In addition to its roles as an enzyme cofactor for cytochrome C oxidase and superoxide dismutase, copper forms complexes with the thiocarbamate disulfiram (DSF) forming DSF-copper complexes, which enhances the DSF-mediated inhibition of the 26S proteasome; proteasome inhibition may result in inhibition of cellular protein degradation, cessation of cell cycle progression, inhibition of cellular proliferation, and the induction of apoptosis in susceptible tumor cell populations.
Solubility Light blue to bluish-green, odorless crystals and crystalline powder. Astringent taste. 30 g soluble in 100 ml water at 25 °C; slightly sol in alcohol; practically insol in most org solvents. /Hydrate/
Formula
C12H22CuO14
Mol. Weight
453.84
CAS #
527-09-3
State
Light blue odorless solid; [HSDB] Light blue powder; [Alfa Aesar MSDS]
See origin →
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Conditions Skin
Skin Protecting
Shields skin from damage
EWG
2
CIR
Pregnancy
CIR Safety Findings
Not an Irritant
all-shades-safe
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG