D-Panthenol (Provitamin B5)
AKA “Provitamin B5
Vitamin B5
Ingredient Facts
D-panthenol (Provitamin B5)
Vitamin B5 · Antioxidant · EWG: 4
Synthetic
Antioxidant
Skin Conditioner
B Vitamin
Vitamin B5
Not Clean
D-Panthenol (Provitamin B5) is a cosmetic ingredient.
Formula
C9H19NO4
Mol. Weight
205.25
CAS #
81-13-0
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Locks in moisture
Accelerates skin healing
Quells irritation
Traditional Use
Pantothenic acid (vitamin B5) was discovered in 1933; D-panthenol was developed in the 1950s as a stable humectant and skin-conditioning ingredient derived from pantothenic acid.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR