Darutoside
AKA “59219-65-7, EG8ODI0780, (2R, 3R, 4S, 5S, 6R)-2-[[(2R, 4aS, 4bR, 7S, 10aS)-7-[(1R)-1, 2-dihydroxyethyl]-1, 1, 4a, 7-tetramethyl-3, 4, 4b, 5, 6, 9, 10, 10a-octahydro-2H-phenanthren-2-yl]oxy]-6-(hydroxymethyl)oxane-3, 5-triol, 6R)-2-(((2R, 10aS)-7-((1R)-1, 2-dihydroxyethyl)-1, 10a-octahydro-2H-phenanthren-2-yl)oxy)-6-(hydroxymethyl)oxane-3, RefChem:130973, 6R)-2-((2R)-2-((2S, 4aR, 4bS, 7R, 8aS)-7-hydroxy-2, 8, 8-tetramethyl-4, 7, 8a, 10-octahydro-3H-phenanthren-2-yl)-2-hydroxyethoxy)-6-(hydroxymethyl)oxane-3, 10aS)-7-((R)-1, 2-Dihydroxyethyl)-1, 7-tetramethyl-1, 2, 3, 10a-dodecahydrophenanthren-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3, Darutin, UNII-EG8ODI0780
Synthetic
Ingredient Facts
Darutoside
AKA: 59219-65-7, EG8ODI0780, (2R, 3R, 4S, 5S, 6R)-2-[[(2R, 4aS, 4bR, 7S, 10aS)-7-[(1R)-1, 2-dihydroxyethyl]-1, 1, 4a, 7-tetramethyl-3, 4, 4b, 5, 6, 9, 10, 10a-octahydro-2H-phenanthren-2-yl]oxy]-6-(hydroxymethyl)oxane-3, 5-triol, 6R)-2-(((2R, 10aS)-7-((1R)-1, 2-dihydroxyethyl)-1, 10a-octahydro-2H-phenanthren-2-yl)oxy)-6-(hydroxymethyl)oxane-3, RefChem:130973, 6R)-2-((2R)-2-((2S, 4aR, 4bS, 7R, 8aS)-7-hydroxy-2, 8, 8-tetramethyl-4, 7, 8a, 10-octahydro-3H-phenanthren-2-yl)-2-hydroxyethoxy)-6-(hydroxymethyl)oxane-3, 10aS)-7-((R)-1, 2-Dihydroxyethyl)-1, 7-tetramethyl-1, 2, 3, 10a-dodecahydrophenanthren-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3, Darutin, UNII-EG8ODI0780
Synthetic · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Synthetic
Clean
from Siegesbeckia glabrescens Mak; RN given refers to (2R-(2alpha,4aalpha,4bbeta,7alpha(R*),10abeta))
Formula
C26H44O8
Mol. Weight
484.60
CAS #
59219-65-7
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Skin
Softens & Smooths
Skin Types
all-skin-types
Best For
General
EWG
1
CIR
Insufficient
Pregnancy
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
CANADApermitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR