Didecyl Ether
AKA “Decyl ether, 2456-28-2, 1-decoxydecane, Decane, 1, 1'-oxybis-, Capric ether, 1'-Oxybisdecane, n-Decyl ether, dicapryl ether, DA81HI310Z”
Skin Conditioning
Ingredient Facts
Didecyl ether
AKA: 2456-28-2, 1-decoxydecane, Decane, 1, 1'-oxybis-, Capric ether, 1'-Oxybisdecane, N-Decyl ether, Dicapryl ether, DA81HI310Z
Skin Conditioning · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Not Clean
Decyl ether has been reported in Lonicera japonica with data available.
Formula
C20H42O
Mol. Weight
298.50
CAS #
2456-28-2
Form
Liquid
State
Low melting solid; [Alfa Aesar MSDS] Liquid; [Sigma-Aldrich MSDS]
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Synthetic volatile emollient created for light-textured cosmetic formulations. Developed as a non-greasy carrier and skin-feel modifier in contemporary cosmetics.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Percutaneous absorption and skin irritation upon low-level prolonged dermal exposure to nonane, dodecane and tetradecane in hairless rats.
Babu RJ, Chatterjee A, Ahaghotu E, Singh M
Toxicology and industrial health, 2004
Pleiotropic Effects of White Willow Bark and 1,2-Decanedi...
Eleonora Bassino, Franco Gasparri, Luca Munaron
Skin pharmacology and physiology, 2018
Pleiotropic Effects of White Willow Bark and 1,2-Decanedi...
Eleonora Bassino, Franco Gasparri, Luca Munaron
Skin pharmacology and physiology, 2018
Anti-Allergic and Anti-Inflammatory Effects of Undecane on Mast Cells and Keratinocytes.
Choi D, Kang W, Park T
Molecules (Basel, Switzerland), 2020
1,10-Decanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Oleamido-1,3-Octadecanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Didecyl Ether
European Commission
EU Cosmetic Ingredient Database (CosIng)
Diisocetyl Dodecanedioate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dioctyldodecyl Dodecanedioate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dodecanedioic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Isododecane
European Commission
EU Cosmetic Ingredient Database (CosIng)
Isohexadecane
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyglyceryl-10 Eicosanedioate/Tetradecanedioate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyglyceryl-10 Tetradecanedioate
European Commission
EU Cosmetic Ingredient Database (CosIng)
The anti-inflammatory and antioxidant properties of 1,2-decanediol and willow bark extract in lipopolysaccharide-stimulated keratinocytes.
Di Caprio R, Monfrecola G, Balato A, Balato N, Gasparri F et al.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2019
1,10-Decanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Oleamido-1,3-Octadecanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Dioctyldodecyl Dodecanedioate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Dodecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Hexadecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isododecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isohexadecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Tetradecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Tridecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Undecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Antitumor efficacy of poly(dimer acid-dodecanedioic acid) copolymer in mice bearing Sarcoma-180 tumor.
Guo WX, Shi Z, Zeng FB, Liang K, Chen XH et al.
Journal of materials science. Materials in medicine, 2007
(64)Cu-1,4,7,10-4,11-Bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane-rhenium-cyclized-[Cys(3,4,10),D-Phe(7),Arg(11)]α-MSH(3-13).
Leung K
, 2004
Fragrance material review on ethylene dodecanedioate.
McGinty D, Letizia CS, Api AM
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011
Comparative in vivo toxicity of topical JP-8 jet fuel and its individual hydrocarbon components: identification of tridecane and tetradecane as key co
Muhammad F, Monteiro-Riviere NA, Riviere JE
Toxicologic pathology, 2005
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR