Diisoamyl Malate
AKA “
Diisopentyl malate, Butanedioic acid, hydroxy-, bis(3-methylbutyl) ester, UNII-V3CNF0D6YT, Diisoamyl malate [INCI], V3CNF0D6YT, Di(3-methylbutyl)hydroxybutanedioate, DTXSID90437907, RefChem:134029, DTXCID60388730
”
Emollient
🦆
❤️
👻
Ingredient Facts
Diisoamyl malate
AKA: Diisopentyl malate, Butanedioic acid, Hydroxy-, Bis(3-methylbutyl) ester, UNII-V3CNF0D6YT, Diisoamyl malate [INCI], V3CNF0D6YT, Di(3-methylbutyl)hydroxybutanedioate, DTXSID90437907, RefChem:134029, DTXCID60388730
Emollient · Emollient · EWG: 4
WHAT IS IT?
Synthetic
Emollient
Solvent
Skin Conditioner
Not Clean
Di(3-methylbutyl)hydroxybutanedioate
Formula
C14H26O5
Mol. Weight
274.35
CAS #
1587-19-5
Form
Liquid
See origin →
WHAT'S IT DO?
Functions
Plasticiser
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Synthetic ester developed as a humectant and skin conditioning agent in cosmetics. Designed to improve hydration and product feel in formulations.
Skin Types
●
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
IS IT SAFE?
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA
✔ permitted
EU
⚠ restricted
JAPAN
⚠ restricted
CANADA
⚠ restricted
Regulatory Agencies
EWG
CIR
FDA
EU COSING
Health Canada
WHAT'S THE PROOF?
Diisoamyl Malate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
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Health Canada
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Effects of 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsor
Limat A, Hunziker T, Braathen LR
Archives of dermatological research, 1993
→
Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by
Yang G, Li S, Yang Y, Yuan L, Wang P et al.
Journal of agricultural and food chemistry, 2018
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Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by
Yang G, Li S, Yang Y, Yuan L, Wang P et al.
Journal of agricultural and food chemistry, 2018
→
Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by
Yang G, Li S, Yang Y, Yuan L, Wang P et al.
Journal of agricultural and food chemistry, 2018
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR