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Diisodecyl Adipate
AKA “27178-16-1, Hexanedioic acid, diisodecyl ester, Adipic acid, Diisodecyl hexanedioate, EINECS 248-299-9, HALLSTAR DIDA, DUB DIDA, 3V0Q382O0P, 1, 6-diisodecyl ester”
Emollient
Ingredient Facts
Diisodecyl adipate
AKA: 27178-16-1, Hexanedioic acid, Diisodecyl ester, Adipic acid, Diisodecyl hexanedioate, EINECS 248-299-9, HALLSTAR DIDA, DUB DIDA, 3V0Q382O0P, 1, 6-diisodecyl ester
Emollient · Emollient · EWG: 4
Synthetic
Emollient
Solvent
Skin Conditioner
Not Clean
Diisodecyl adipate
Formula
C26H50O4
Mol. Weight
426.70
CAS #
27178-16-1
Form
Liquid
State
Pellets or Large Crystals; Liquid
See origin →
Functions
Plasticiser
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Synthetic emollient developed for use in cosmetics as a non-greasy conditioning agent. Created in the 20th century to improve formulation stability compared to plant oils.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Final Report on the Safety Assessment of Adipic Acid Dihydrazide
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
1,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid/CHDM/MA/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Diisodecyl Adipate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Toxicity of adipic acid.
Kennedy GL Jr
Drug and chemical toxicology, 2002
→
Allergic Contact Dermatitis to Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer in a Lip Balm.
Lockmann A, Schill T, Schubert S, Buhl T
Contact dermatitis, 2026
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR