Diisooctyl Adipate
AKA “
HEXANEDIOIC ACID, BIS(1-METHYLHEPTYL) ESTER, Bis(1-methylheptyl) adipate, Adipic acid, bis(1-methylheptyl) ester, CASMATE DCA, HALLSTAR DCA, NSC 6197
”
Synthetic
🦆
❤️
👻
Ingredient Facts
Diisooctyl adipate
AKA: HEXANEDIOIC ACID, BIS(1-METHYLHEPTYL) ESTER, Bis(1-methylheptyl) adipate, Adipic acid, Bis(1-methylheptyl) ester, CASMATE DCA, HALLSTAR DCA, NSC 6197
Synthetic · Emollient · EWG: 4
WHAT IS IT?
Synthetic
Emollient
Solvent
Skin Conditioner
Synthetic
Clean
A lightweight emollient that softens and smooths skin while helping other ingredients blend seamlessly into the formula.
Formula
C22H42O4
Mol. Weight
370.60
CAS #
108-63-4
Form
Liquid
State
Liquid
See origin →
WHAT'S IT DO?
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Synthetic emollient ester formulated for cosmetic skin conditioning. Designed to provide lightweight moisture and smooth product application.
Skin Types
●
all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
IS IT SAFE?
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA
under review
EU
⚠ restricted
JAPAN
⚠ restricted
CANADA
⚠ restricted
Regulatory Agencies
EWG
CIR
FDA
EU COSING
Health Canada
WHAT'S THE PROOF?
Final Report on the Safety Assessment of Adipic Acid Dihydrazide
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
1,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid/CHDM/MA/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Diisooctyl Adipate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Diisooctyl Adipate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Toxicity of adipic acid.
Kennedy GL Jr
Drug and chemical toxicology, 2002
→
Allergic Contact Dermatitis to Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer in a Lip Balm.
Lockmann A, Schill T, Schubert S, Buhl T
Contact dermatitis, 2026
→
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR