Diisooctyl Adipate
AKA “108-63-4, HEXANEDIOIC ACID, BIS(1-METHYLHEPTYL) ESTER, Bis(1-methylheptyl) adipate, 2TLQ9O0CWB, Adipic acid, bis(1-methylheptyl) ester, CASMATE DCA, HALLSTAR DCA, NSC 6197, NSC-6197, EINECS 203-601-8”
Emollient
Ingredient Facts
Diisooctyl adipate
AKA: 108-63-4, HEXANEDIOIC ACID, BIS(1-METHYLHEPTYL) ESTER, Bis(1-methylheptyl) adipate, 2TLQ9O0CWB, Adipic acid, Bis(1-methylheptyl) ester, CASMATE DCA, HALLSTAR DCA, NSC 6197, NSC-6197, EINECS 203-601-8
Emollient · Emollient · EWG: 1
Synthetic
Emollient
Solvent
Skin Conditioner
Clean
Hexanedioic Acid, Bis-(1-Methylheptyl) Ester
Formula
C22H42O4
Mol. Weight
370.60
CAS #
108-63-4
Form
Liquid
State
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Synthetic emollient ester formulated for cosmetic skin conditioning. Designed to provide lightweight moisture and smooth product application.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Final Report on the Safety Assessment of Adipic Acid Dihydrazide
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
1,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid/CHDM/MA/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Diisooctyl Adipate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Adipic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Diisooctyl Adipate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Toxicity of adipic acid.
Kennedy GL Jr
Drug and chemical toxicology, 2002
Allergic Contact Dermatitis to Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer in a Lip Balm.
Lockmann A, Schill T, Schubert S, Buhl T
Contact dermatitis, 2026
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR