Diisopropyl Sebacate
AKA “7491-02-3, Decanedioic acid, bis(1-methylethyl) ester, Bis(1-methylethyl)decanedioate, J8T3X564IH, DERMOL DIPS, DTXSID3064720, RefChem:134073, bis(1-methylethyl) decanedioate, DTXCID3047716
Emollient
Ingredient Facts
Diisopropyl sebacate
AKA: 7491-02-3, Decanedioic acid, Bis(1-methylethyl) ester, Bis(1-methylethyl)decanedioate, J8T3X564IH, DERMOL DIPS, DTXSID3064720, RefChem:134073, Bis(1-methylethyl) decanedioate, DTXCID3047716
Emollient · Emollient · EWG: 1
Synthetic
Emollient
Solvent
Skin Conditioner
Clean
vehicle in topical anti-acne lotion; implicated in contact dermatitis; structure given in first source
Formula
C16H30O4
Mol. Weight
286.41
CAS #
7491-02-3
Form
Liquid
See origin →
Functions
Plasticiser
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Developed as a synthetic ester in the mid-20th century. Used in cosmetics as a lightweight emollient and conditioning agent designed to mimic the feel of natural sebaceous secretions.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR