Dioctyldodecyl Malate
AKA “Salacos 20M, Di-2-octyldodecyl malate, UNII-CU2P94S7NW, CU2P94S7NW, 63623-64-3, Butanedioic acid, hydroxy-, bis(2-octyldodecyl) ester, 2-hydroxy-, 1, 4-bis(2-octyldodecyl) ester, RefChem:134505, DIOCTYLDODECYL MALATE [INCI]
Skin Conditioning
Ingredient Facts
Dioctyldodecyl malate
AKA: Salacos 20M, Di-2-octyldodecyl malate, UNII-CU2P94S7NW, CU2P94S7NW, 63623-64-3, Butanedioic acid, Hydroxy-, Bis(2-octyldodecyl) ester, 2-hydroxy-, 1, 4-bis(2-octyldodecyl) ester, RefChem:134505, DIOCTYLDODECYL MALATE [INCI]
Skin Conditioning · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Not Clean
Di-(2-Octyldodecyl) 2-hydroxybutanedioate
Formula
C44H86O5
Mol. Weight
695.10
CAS #
-
Form
Oil
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic ester developed for cosmetic formulations. Functions as an emollient and conditioning ingredient with no traditional medicinal use.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Dioctyldodecyl Malate
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Effects of 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsor
Limat A, Hunziker T, Braathen LR
Archives of dermatological research, 1993
Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by
Yang G, Li S, Yang Y, Yuan L, Wang P et al.
Journal of agricultural and food chemistry, 2018
Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by
Yang G, Li S, Yang Y, Yuan L, Wang P et al.
Journal of agricultural and food chemistry, 2018
Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR