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Dipropyl Adipate
AKA “DIPROPYL HEXANEDIOATE, Adipic acid, dipropyl ester, Adipic acid di-n-propyl ester, 1, 6-dipropyl hexanedioate, di-n-propyl ester, NSC 4894, EINECS 203-371-9, UNII-WB3LW508W0, BRN 1785512”
Emollient
Ingredient Facts
Dipropyl adipate
AKA: DIPROPYL HEXANEDIOATE, Adipic acid, Dipropyl ester, Adipic acid di-n-propyl ester, 1, 6-dipropyl hexanedioate, Di-n-propyl ester, NSC 4894, EINECS 203-371-9, UNII-WB3LW508W0, BRN 1785512
Emollient · Emollient · EWG: 4
Synthetic
Emollient
Solvent
Skin Conditioner
Not Clean
Dipropyl hexanedioate is a fatty acid ester.
Solubility very slightly
Formula
C12H22O4
Mol. Weight
230.30
CAS #
106-19-4
Form
Liquid
State
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
A synthetic ester developed in the mid-20th century for cosmetic use. Designed as an emollient and solvent to improve spreadability and sensory feel of skincare and cosmetic products.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Final Report on the Safety Assessment of Adipic Acid Dihydrazide
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
1,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid/CHDM/MA/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Dipropyl Adipate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Adipic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Adipic Acid/Neopentyl Glycol/Trimellitic Anhydride Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Toxicity of adipic acid.
Kennedy GL Jr
Drug and chemical toxicology, 2002
→
Allergic Contact Dermatitis to Trimethylpentanediol/Adipic Acid/Glycerin Crosspolymer in a Lip Balm.
Lockmann A, Schill T, Schubert S, Buhl T
Contact dermatitis, 2026
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR