Disodium EDTA
AKA “139-33-3, EDTA disodium salt, Edta disodium, Titriplex III, Disodium edta, anhydrous, Endrate disodium, Disodium ethylenediaminetetraacetate, Edetic Acid, Disodium Salt, Ethylenediaminetetraacetic acid, disodium salt”
Ingredient
Ingredient Facts
Disodium edta
AKA: 139-33-3, EDTA disodium salt, Edta disodium, Titriplex III, Anhydrous, Endrate disodium, Disodium ethylenediaminetetraacetate, Edetic Acid, Disodium Salt, Ethylenediaminetetraacetic acid, Disodium salt
Ingredient · Chelating · EWG: 2
Synthetic
Chelating Agent
Clean
Disodium dihydrogen ethylenediaminetetraacetate
Formula
C10H14N2Na2O8
Mol. Weight
336.21
CAS #
139-33-3, 6381-92-6
Form
Powder
State
Liquid; Dry Powder; Other Solid
See origin →
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Viscosity Controlling
Antioxidant
Anti-Inflammatory
Boosts Collagen
Binds metal ions
Controls product thickness
Traditional Use
Synthetic chelating agent developed in the 1930s-1940s as an alternative to natural phosphates; used in cosmetics to bind metal ions and prevent product degradation and oxidation.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
2
CIR
Reviewed by CIR
Pregnancy
Yes
CIR Safety Findings
all-shades-safe
Regulatory Agencies
Final Report on the Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, HEDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, and Trisod
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Calcium Disodium EDTA
European Commission
EU Cosmetic Ingredient Database (CosIng)
Disodium EDTA
European Commission
EU Cosmetic Ingredient Database (CosIng)
Calcium Disodium EDTA
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Disodium EDTA
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tr
Lanigan RS, Yamarik TA
International journal of toxicology, 2002
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR