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Disodium Phosphate
AKA “7558-79-4, Sodium phosphate dibasic, Disodium hydrogen phosphate, Disodium hydrogenorthophosphate, Acetest, Sodium phosphate, dibasic, Dibasic sodium phosphate, Disodium acid phosphate, disodium hydrogenphosphate”
Ingredient
Ingredient Facts
Disodium phosphate
AKA: 7558-79-4, Sodium phosphate dibasic, Disodium hydrogen phosphate, Disodium hydrogenorthophosphate, Acetest, Dibasic, Dibasic sodium phosphate, Disodium acid phosphate, Disodium hydrogenphosphate
Ingredient · Anticorrosive · EWG: 1
Synthetic
Clean
Disodium hydrogenorthophosphate
Solubility greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Formula
HNa2O4P
Mol. Weight
141.96
CAS #
7558-79-4, 7782-85-6
Form
Powder
State
Sodium phosphate, dibasic appears as a colorless to white crystalline solid. Soluble in water. The primary hazard is the threat to the environment. Immediate steps should be taken to limit spread to t
See origin →
Functions
Anticorrosive
Buffering
Antioxidant
Anti-Inflammatory
Boosts Collagen
Provides scent
Prevents product degradation
Maintains optimal pH
Traditional Use
Discovered as a naturally occurring phosphate compound in the 18th-19th century. First used in cosmetics as a pH buffer and chelating agent in mid-20th century formulations.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Calcium Potassium Sodium Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Disodium Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Trisodium Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Disodium Phosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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Sodium Phosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Trisodium Phosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug.
Grosios K, Holwell SE, McGown AT, Pettit GR, Bibby MC
British journal of cancer, 1999
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Trisodium Phosphate and Cetylpyridinium Chloride Spraying on Chicken Skin to Reduce Attached Salmonella typhimurium.
Wang WC, Li Y, Slavik MF, Xiong H
Journal of food protection, 1997
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR