DMDM Hydantoin
AKA “6440-58-0, Dmdmh, Glydant, 1, 3-Bis(hydroxymethyl)-5, 5-dimethylhydantoin, 3-Dimethylol-5, Dantoin-DMDMH, Glycoserve-DMDMH, Dantoin dmdmh 55, Dimethylol-5
Preservative
Ingredient Facts
Dmdm hydantoin
AKA: 6440-58-0, Dmdmh, Glydant, 1, 3-Bis(hydroxymethyl)-5, 5-dimethylhydantoin, 3-Dimethylol-5, Dantoin-DMDMH, Glycoserve-DMDMH, Dantoin dmdmh 55, Dimethylol-5
Preservative · Preservative · EWG: 6
Synthetic
Preservative
Not Clean
1,3-bis(Hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
Solubility In water, 77.3 g/100 cc
Formula
C7H12N2O4
Mol. Weight
188.18
CAS #
6440-58-0
Form
Liquid
State
Liquid
See origin →
Functions
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Preserves Formula
Antioxidant Protection
Reduces Inflammation
Locks In Moisture
Prevents microbial growth
Traditional Use
Developed in the mid-20th century as a synthetic preservative and formaldehyde releaser. Created to prevent microbial growth in cosmetics and personal care products, it was widely adopted in the 1970s-1980s before regulatory scrutiny increased due to formaldehyde release concerns.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Allergen Warning
⚠️ Formaldehyde Releaser
EWG
6
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Concentration Guide
0.6%
0%1%
Reg. Limit
EU regulatory limit: 0.6%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex V (Preservatives), Entry 33.
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR