Dodecane
AKA “n-Dodecane, 112-40-3, Dihexyl, Bihexyl, Adakane 12, N-Dodecan, Duodecane, Ba 51-090453, DTXSID0026913
Ingredient Facts
Dodecane
AKA: N-Dodecane, 112-40-3, Dihexyl, Bihexyl, Adakane 12, N-Dodecan, Duodecane, Ba 51-090453, DTXSID0026913
Synthetic · Emollient · EWG: 1
Synthetic
Emollient
Clean
Dodecane is a straight-chain alkane with 12 carbon atoms. It has been isolated from the essential oils of various plants including Zingiber officinale (ginger). It has a role as a plant metabolite.
Solubility less than 1 mg/mL at 77 °F (NTP, 1992)
Formula
C12H26
Mol. Weight
170.33
CAS #
112-40-3
State
N-dodecane is a clear colorless liquid. (NTP, 1992)
See origin →
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Perfuming
Skin Types
all-skin-types
Best For
General
EWG
1
CIR
Insufficient
Pregnancy
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
CANADApermitted
Regulatory Agencies
Percutaneous absorption and skin irritation upon low-level prolonged dermal exposure to nonane, dodecane and tetradecane in hairless rats.
Babu RJ, Chatterjee A, Ahaghotu E, Singh M
Toxicology and industrial health, 2004
Dihexyl Adipate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dihexyl Sodium Sulfosuccinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dihexyldecyl Adipate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dihexyldecyl Sebacate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Diisocetyl Dodecanedioate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dioctyldodecyl Dodecanedioate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dodecanedioic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Isododecane
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dioctyldodecyl Dodecanedioate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Dodecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isododecane
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Antitumor efficacy of poly(dimer acid-dodecanedioic acid) copolymer in mice bearing Sarcoma-180 tumor.
Guo WX, Shi Z, Zeng FB, Liang K, Chen XH et al.
Journal of materials science. Materials in medicine, 2007
Fragrance material review on ethylene dodecanedioate.
McGinty D, Letizia CS, Api AM
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR