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Ethyl Ferulate
AKA “4046-02-0, Ethyl 4-hydroxy-3-methoxycinnamate, ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate, Ferulic acid, ethyl ester, 5B8915UELW, ORISTRACT EF, NOMCORT EF, NSC-14879, ETHYL 4'-HYDROXY-3'-METHOXYCINNAMAT”
Synthetic
Ingredient Facts
Ethyl ferulate
AKA: 4046-02-0, Ethyl 4-hydroxy-3-methoxycinnamate, Ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate, Ferulic acid, Ethyl ester, 5B8915UELW, ORISTRACT EF, NOMCORT EF, NSC-14879, ETHYL 4'-HYDROXY-3'-METHOXYCINNAMAT
Synthetic · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Synthetic
Clean
Ethyl ferulate has been reported in Spiraea formosana, Coptis japonica, and other organisms with data available.
Formula
C12H14O4
Mol. Weight
222.24
CAS #
4046-02-0
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Antioxidant Protection
Neutralizes Free Radicals
Traditional Use
CAS number for Cetyl Alcohol, a fatty alcohol derived from plant or animal sources. Historically used in traditional cosmetics as an emollient and thickening agent before synthetic production became standard in the mid-20th century.
Skin Types
●all-skin-types
Best For
General
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
RIFM fragrance ingredient safety assessment, pentanedioic acid, 1,5-dimethyl ester, CAS Registry Number 1119-40-0.
Api AM, Belsito D, Botelho D, Browne D, Bruze M et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018
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Final Report on the Safety Assessment of Ethyl Ester of PVM/MA Copolymer and Butyl Ester of PVM/MA Copolymer
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Ethyl Ester of PVM/MA Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Potassium Ethyl Ester of PVM/MA Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Shea Butter Ethyl Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Silybum marianum ethyl ester
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions.
Cunha FVM, Coelho AG, Azevedo PSDS, da Silva AA Júnior, Oliveira FA et al.
Expert opinion on therapeutic patents, 2019
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Ethyl Ester of PVM/MA Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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Ethyl Ferulate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Ferulic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Shea Butter Ethyl Esters
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Detection of fatty acid ethyl esters in skin surface lipids as biomarkers of ethanol consumption in alcoholics, social drinkers, light drinkers, and t
González-Illán F, Ojeda-Torres G, Díaz-Vázquez LM, Rosario O
Journal of analytical toxicology, 2011
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3-Imidazol-4-ylacrylic acid and its ethyl ester
Health Canada
Health Canada Cosmetic Ingredient Hotlist
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Synthesis of mixed esters of ascorbic acid using methyl esters of palm and soybean oils.
Hsieh HJ, Chen JW, Giridhar R, Wu WT
Preparative biochemistry & biotechnology, 2005
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Multifunctional carbomer based ferulic acid hydrogel promotes wound healing in radiation-induced skin injury by inactivating NLRP3 inflammasome.
Huang C, Huangfu C, Bai Z, Zhu L, Shen P et al.
Journal of nanobiotechnology, 2024
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Multifunctional carbomer based ferulic acid hydrogel prom...
Congshu Huang, Chaoji Huangfu, Zhijie Bai, Long Zhu, Pan Shen, Ningning Wang + 5 more
Journal of nanobiotechnology, 2024
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Ferulic acid stabilizes a solution of vitamins C and E an...
Fu-Hsiung Lin, Jing-Yi Lin, Ravindra D Gupta, Joshua A Tournas, James A Burch, M Angelica Selim + 4 more
The Journal of investigative dermatology, 2005
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Formulation and evaluation of a water-in-oil cream containing herbal active ingredients and ferulic acid.
Moldovan M, Lahmar A, Bogdan C, Părăuan S, Tomuţă I et al.
Clujul medical (1957), 2017
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Formulation and evaluation of a water-in-oil cream containing herbal active ingredients and ferulic acid.
Moldovan M, Lahmar A, Bogdan C, Părăuan S, Tomuţă I et al.
Clujul medical (1957), 2017
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Formulation and evaluation of a water-in-oil cream containing herbal active ingredients and ferulic acid.
Moldovan M, Lahmar A, Bogdan C, Părăuan S, Tomuţă I et al.
Clujul medical (1957), 2017
→
Stability and Anti-Aging of Encapsulated Ferulic Acid in Phosphorylated Rice Starch.
Pueknang J, Saewan N
Molecules (Basel, Switzerland), 2022
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Stability and Anti-Aging of Encapsulated Ferulic Acid in Phosphorylated Rice Starch.
Pueknang J, Saewan N
Molecules (Basel, Switzerland), 2022
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Antioxidant Properties of Ferulic Acid and Its Possible Application.
Zduńska K, Dana A, Kolodziejczak A, Rotsztejn H
Skin pharmacology and physiology, 2018
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR