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Glucose
AKA “D-Glucopyranose, Glucopyranose, Blood sugar, (3R, 6R)-6-(hydroxymethyl)oxane-2, 5-tetrol, Grape sugar, D-Glc”
Ingredient Facts
Glucose
AKA: D-Glucopyranose, Glucopyranose, Blood sugar, (3R, 6R)-6-(hydroxymethyl)oxane-2, 5-tetrol, Grape sugar, D-Glc
Synthetic · Humectant · EWG: 1
Synthetic
Humectant
Skin Conditioner
Clean
A natural humectant that draws moisture into skin, helping it stay hydrated and plump throughout the day.
Effective at 48.9%
Solubility Soluble
Formula
C6H12O6
Mol. Weight
180.16
CAS #
50-99-7
Form
Powder
State
Watery odorless colorless liquid. Denser than water and soluble in water. Hence sinks in and mixes with water. (USCG, 1999)
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
Traditional Use
A simple sugar, glucose was first isolated in the 19th century. Used in modern cosmetics for humectancy; historically obtained from honey and fruits in traditional preparations.
Skin Types
●all-skin-types, gentle
Best For
Dehydration
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Concentration Guide
3e-05%
97.8%
0%100%
Effective Range
CIR reported use: 0.0001-0.18 | 0.00003-97.8
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Double Polishing Peel
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Day & Night Fundamentals
Odacité
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Day & Night Eye Care Duo
Odacité
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The New Tendency Duo
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The New Tendency Complete Set
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The Body Essentials
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The Body Lotion 70 ml | Multi-Peptide | Olibanum
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Final Report on the Safety Assessment of Glucose Glutamate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Methyl Glucose Polyethers and Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Allergic contact dermatitis due to methyl glucose dioleate.
Corazza M, Levratti A, Virgili A
Contact dermatitis, 2001
→
Cyclotetraglucose
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Disodium Glucose Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glucose
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glucose Glutamate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glucose Pentaacetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Caprylate/Caprate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Dioleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Isostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Sesquicaprylate/Sesquicaprate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Sesquicocoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Sesquiisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Sesquilaurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Sesquioleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Glucose Sesquistearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-120 Methyl Glucose Dioleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-120 Methyl Glucose Triisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-120 Methyl Glucose Trioleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Methyl Glucose Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Methyl Glucose Sesquicaprylate/Sesquicaprate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Methyl Glucose Sesquilaurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Methyl Glucose Sesquistearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-80 Methyl Glucose Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PPG-10 Methyl Glucose Ether
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PPG-20 Methyl Glucose Ether
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PPG-20 Methyl Glucose Ether Acetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PPG-20 Methyl Glucose Ether Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PPG-25 Methyl Glucose Ether
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
sodium lauryl glucose carboxylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glucose
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glucose Pentaacetate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Methyl Glucose Caprylate/Caprate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Methyl Glucose Dioleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Methyl Glucose Sesquistearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-120 Methyl Glucose Dioleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-120 Methyl Glucose Trioleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-20 Methyl Glucose Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-20 Methyl Glucose Sesquistearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PPG-10 Methyl Glucose Ether
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PPG-20 Methyl Glucose Ether
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PPG-20 Methyl Glucose Ether Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
sodium lauryl glucose carboxylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Safety Assessment of Methyl Glucose Polyethers and Esters as Used in Cosmetics.
Johnson W Jr, Heldreth B, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2016
→
Safety Assessment of Methyl Glucose Polyethers and Esters as Used in Cosmetics.
Johnson W Jr, Heldreth B, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2016
→
Traditionally Used Plants in the Treatment of Diabetes Mellitus: Screening for Uptake Inhibition of Glucose and Fructose in the Caco2-Cell Model.
Schreck K, Melzig MF
Frontiers in pharmacology, 2021
→
Jingfang Granules improve glucose metabolism disturbance and inflammation in mice with urticaria by up-regulating LKB1/AMPK/SIRT1 axis.
Sun C, Liang H, Zhao Y, Li S, Li X et al.
Journal of ethnopharmacology, 2023
→
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR