Glyceryl Hydroxystearate
AKA “Octadecanoic acid, hydroxy-, monoester with 1, 2, 3-propanetriol, 1323-42-8, UJ6CAW9YNV, Stearic acid, monoester with glycerol, Hydroxyoctadecanoic acid, EINECS 215-355-9, Hydroxystearic acid, RefChem:663534, glyceryl monohydroxy stearate, DTXSID9051666
Surfactant
Ingredient Facts
Glyceryl hydroxystearate
AKA: Octadecanoic acid, Hydroxy-, Monoester with 1, 2, 3-propanetriol, 1323-42-8, UJ6CAW9YNV, Stearic acid, Monoester with glycerol, Hydroxyoctadecanoic acid, EINECS 215-355-9, Hydroxystearic acid, RefChem:663534, Glyceryl monohydroxy stearate, DTXSID9051666
Surfactant · Emollient · EWG: 3
Plant-Derived
Emollient
Cleanser
Emulsifier
Skin Conditioner
Plant Oil
Not Clean
Hydroxyoctadecanoic acid, monoester with glycerol
Formula
C21H42O5
Mol. Weight
374.60
CAS #
1323-42-8
Form
Wax
See origin →
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks In Moisture
Traditional Use
Synthetic ester developed as a skin conditioning and emulsifying agent. Created to provide both hydrophobic and hydrophilic properties in cosmetic formulations.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
3
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Amended Final Report on the Safety Assessment of Hydroxystearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Isostearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report: Safety Assessment of Polyhydroxystearic Acid, Poly(3-Hydroxyoctanoic Acid, and Polylactic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Re-evaluation: Safety Assessment of Hydroxystearic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
10-Hydroxystearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glyceryl Hydroxystearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyhydroxystearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Stearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glyceryl Hydroxystearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Hydroxystearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isostearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Polyhydroxystearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Stearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2,4-Dihydroxy-3-methylbenzaldehyde
Health Canada
Health Canada Cosmetic Ingredient Hotlist
4,4'-Dihydroxy-3,3'-(3-methylthiopropylidene) dicoumarin
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Toluidines, their isomers, salts and halogenated and sulfonated derivatives except 4-hydroxy-2-nitro-toluidine and hydroxyethyl-2-nitro-p-toluidine
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Simultaneous contact sensitivity to hydroxystearic acid and C18-36 acid triglyceride in lip glosses.
Kimura M, Kawada A, Ogino M, Murayama Y
Contact dermatitis, 2002
Effects of 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsor
Limat A, Hunziker T, Braathen LR
Archives of dermatological research, 1993
Microemulsions based on TPGS and isostearic acid for imiquimod formulation and skin delivery.
Pescina S, Garrastazu G, Del Favero E, Rondelli V, Cantù L et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by
Yang G, Li S, Yang Y, Yuan L, Wang P et al.
Journal of agricultural and food chemistry, 2018
Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by
Yang G, Li S, Yang Y, Yuan L, Wang P et al.
Journal of agricultural and food chemistry, 2018
Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by
Yang G, Li S, Yang Y, Yuan L, Wang P et al.
Journal of agricultural and food chemistry, 2018
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR