HC Yellow No. 4
AKA “2-((2-(2-Hydroxyethoxy)-4-nitrophenyl)amino)ethanol, O-Di(2-hydroxyethyl)-2-amino-5-nitrophenol, HC Yellow 4, Ethanol, Colorex HCY4, 2-(3-Nitro-6-(beta-hydroxyethylamino)phenoxy)ethanol
Synthetic
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Ingredient Facts
Hc yellow no. 4
AKA: 2-((2-(2-Hydroxyethoxy)-4-nitrophenyl)amino)ethanol, O-Di(2-hydroxyethyl)-2-amino-5-nitrophenol, HC Yellow 4, Ethanol, Colorex HCY4, 2-(3-Nitro-6-(beta-hydroxyethylamino)phenoxy)ethanol
Synthetic · Hair Dyeing | Colorant · EWG: 4
Plant-Derived
Colorant
Synthetic
Clean
A synthetic colorant that creates vibrant yellow tones in hair dye formulations, delivering consistent, long-lasting color results.
Solubility less than 0.1 mg/mL at 68.9 °F (NTP, 1992)
Formula
C10H14N2O5
Mol. Weight
242.23
CAS #
59820-43-8
Form
Powder
Plant-Derived
Synthetic. HC Yellow No. 4 belongs to the azo dye chemical family, synthesized from aromatic compounds and nitrogen-containing precursors. It is produced through diazotization and coupling reactions of aniline derivatives to create the stable yellow colorant.
Function
Hair Dyeing | Colorant
Benefits
Hair Dyeing
Colors Hair
Traditional Use
A synthetic aromatic dye created for hair coloring applications in the 20th century, designed to provide yellow coloration in semi-permanent hair color formulations with good stability.
Skin Types
all-skin-types
Best For
Target
General
Melanin-Rich Skin
Suitable
Pregnancy Safe
Caution
EWG Score4
CIR Safety Findings
medical-approval, all-shades-safe, Phototoxicity Concern
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Safety review of phenoxyethanol when used as a preservati...
B Dréno, T Zuberbier, C Gelmetti, G Gontijo, M Marinovich
Journal of the European Academy of Dermatology and Venereology : JEADV, 2019
Safety Assessment of Diethanolamine and Its Salts as Used...
Monice M Fiume, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen + 6 more
International journal of toxicology, 2017
Safety Assessment of Diethanolamine and Its Salts as Used...
Monice M Fiume, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen + 6 more
International journal of toxicology, 2017
Safety Assessment of Diethanolamine and Its Salts as Used...
Monice M Fiume, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen + 6 more
International journal of toxicology, 2017
Phenoxyethanol Safety Assessment
Cosmetic Ingredient Review Expert Panel
International Journal of Toxicology, 2019
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR