Hexyl Salicylate
AKA “6259-76-3, N-HEXYL SALICYLATE, 1-Hexyl salicylate, Benzoic acid, 2-hydroxy-, hexyl ester, 8F78EY72YL, DTXSID4038924, DTXCID601473521, RefChem:788304, 228-408-6”
Ingredient
Ingredient Facts
Hexyl salicylate
AKA: 6259-76-3, N-HEXYL SALICYLATE, 1-Hexyl salicylate, Benzoic acid, 2-hydroxy-, Hexyl ester, 8F78EY72YL, DTXSID4038924, DTXCID601473521, RefChem:788304, 228-408-6
Ingredient · Perfuming · EWG: 3
Synthetic
Fragrance
Chemical Exfoliant
Not Clean
Benzoic Acid, 2-hydroxy-, 2-hexyl ester
Formula
C13H18O3
Mol. Weight
222.28
CAS #
6259-76-3
Form
Liquid
State
Liquid; Dry Powder, Liquid, Other Solid
See origin →
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Antioxidant
Anti-Inflammatory
Moisturizing
Provides scent
Traditional Use
A synthetic ester developed as a fragrance ingredient and mild exfoliating agent in modern cosmetics. Created to provide both scent and gentle keratolytic benefits in skincare formulations.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
EWG
3
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Concentration Guide
0.001%
0%0%
Reg. Limit
EU/SCCS limit: 0.001% in children. Opinion: SCCS/1668/24
Regulatory Agencies
Benzyl Alcohol, Benzoic Acid, Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.
Corral-Sarasa J, Martínez-Gálvez JM, González-García P, Wendling O, Jiménez-Sánchez L et al.
Cell reports, 2024
4-Hydroxybenzoic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ethylhexyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Hexyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
4-Hydroxybenzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Benzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Hexyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
Fragrance material review on hexyl salicylate.
Lapczynski A, Jones L, McGinty D, Bhatia S, Letizia CS et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007
Addendum to the Scientific Opinion on Hexyl Salicylate SCCS/1658/23 (CAS/EC No. 6259-76-3/228-408-6) - Children exposure 0-3 years old
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR