Hydrofluorocarbon 152a
AKA “1, 1-DIFLUOROETHANE, 75-37-6, Ethylidene fluoride, Ethylidene difluoride, Ethane, 1-difluoro-, HFC-152a, Genetron 152a, Algofrene type 67, Freon 152a, Propellant 152a
Ingredient
Ingredient Facts
Hydrofluorocarbon 152a
AKA: 1-DIFLUOROETHANE, 75-37-6, Ethylidene fluoride, Ethylidene difluoride, Ethane, 1-difluoro-, HFC-152a, Genetron 152a, Algofrene type 67, Freon 152a, Propellant 152a
Ingredient · Propellant · EWG: 1
Synthetic
Clean
1,1-Difluoroethane is colorless, odorless gas shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. It is easily ignited. Its vapors are heavier than air and a flame can travel back to the source of leak very easily. This leak can be either a liquid or vapor leak. It can asphyxiate by the displacement of air. Under prolonged exposure to fire or heat the containers may rupture violently and rocket.
Solubility In water, 3.2X10+3 mg/L at 25 °C
Formula
C2H4F2
Mol. Weight
66.05
CAS #
75-37-6
Form
Liquid
State
1,1-Difluoroethane is colorless, odorless gas shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. It is easily ignited. Its vapors are heavier than air an
See origin →
Functions
Propellant
Dispenses Product
Propels product from container
Traditional Use
Developed in the 1970s as a hydrofluorocarbon propellant to replace chlorofluorocarbons (CFCs) that depleted ozone. Used in aerosol cosmetics as a non-flammable, volatile solvent.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Polyurethane Versus Calcium Alginate Dressings for Split-Thickness Skin Graft Donor Site: A Systematic Review and Meta-Analysis.
Alsaif A, Karam M, Aldubaikhi AA, Alghufaily A, Alhuwaishel K et al.
Cureus, 2021
Safety Assessment of Hydrofluorocarbon 152a as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2022
Bactericidal ZnO glass-filled thermoplastic polyurethane and polydimethyl siloxane composites to inhibit biofilm-associated infections.
Cabal B, Sevillano D, Fernández-García E, Alou L, Suárez M et al.
Scientific reports, 2019
Final Report on the Safety Assessment of Trichloroethane
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report: Safety Assessment of Polyurethanes as Used as Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Hydrofluorocarbon 152a as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Hydrofluorocarbon 152a
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-11
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-12
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-13
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-15
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-16
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-17
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-2
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-20
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-21
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-23
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-25
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-26
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-27
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-28
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-32
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-33
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-34
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-35
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-36
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-39
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-4
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-40
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-41
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-42
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-43
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-44
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-45
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-47
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-48
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-49
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-5
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-50
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-51
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-52
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-53
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-54
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-55
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-56
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-57
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-58
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-59
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-60
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-61
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-62
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-63
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-64
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-65
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-66
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-67
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-68
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-7
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-8
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyurethane-9
European Commission
EU Cosmetic Ingredient Database (CosIng)
Sodium Octoxynol-2 Ethane Sulfonate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Trichloroethane
European Commission
EU Cosmetic Ingredient Database (CosIng)
Hydrofluorocarbon 152a
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Polyurethane-11
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Polyurethane-15
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Polyurethane-2
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Polyurethane-35
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Chloroethane
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Dichloroethanes
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Hexachloroethane
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Pentachloroethane
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Trichloronitromethane
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Investigations on metabolism and carcinogenicity of 1,1,2-trichloroethane.
Norpoth K, Heger M, Müller G, Mohtashamipur E, Kemena A et al.
Journal of cancer research and clinical oncology, 1988
Encapsulation of the UV filters ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles: effect on in vivo human skin pe
Scalia S, Mezzena M, Ramaccini D
Skin pharmacology and physiology, 2011
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR