Hydrolyzed Fibronectin
AKA “Fibronectin Hydrolysate, Soluble Fibronectin
Skin Conditioning
Ingredient Facts
Hydrolyzed fibronectin
AKA: Fibronectin Hydrolysate, Soluble Fibronectin
Skin Conditioning · Hair Conditioning · EWG: 1
Synthetic
Skin Conditioner
Hair Care
Clean
Protein hydrolyzates, fibronectin. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of fibronectin composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin
Effective at 8.25%
CAS #
100085-35-6
Form
Powder
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Fibronectin is a human protein identified in the 1970s; the hydrolyzed form was later developed for cosmetics as a modern ingredient to support skin matrix and conditioning properties.
Skin Types
all-skin-types
Best For
Loss of Elasticity
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
4e-06%
16.5%
0%100%
Effective Range
CIR reported use: 0.000004-6 | 0.00003-16.5
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: CosIng · EWG · CIR