Hydrolyzed Human Placental Protein
AKA “Placental Protein Hydrolysate, Placenta Extract
Skin Conditioning
Ingredient Facts
Hydrolyzed human placental protein
AKA: Placental Protein Hydrolysate, Placenta Extract
Skin Conditioning · Antistatic · EWG: 3
Synthetic
Skin Conditioner
Hair Care
Not Clean
Protein hydrolyzates, placenta. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of placenta composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin.
CAS #
91080-01-2
Form
Powder
State
Solid
See origin →
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Placental extracts became popular in Japanese and Korean skincare in the mid-20th century, believed to promote cell regeneration and youthfulness. Hydrolyzed human placental protein was developed as a refined cosmetic ingredient to deliver growth factors and amino acids in a more stable, bioavailable form.
Skin Types
all-skin-types
Best For
Loss of Elasticity
Pregnancy & Breastfeeding Safe
Caution
EWG
3
CIR
Insufficient data
Pregnancy
Caution
CIR Safety Findings
all-shades-safe
Potential Sensitizer
Regulatory Status
USAunder review
EUpermitted
JAPANpermitted
CANADApermitted
Final Report on the Safety Assessment of Human Placental Protein, Hydrolyzed Human Placental Protein, Human Placental Enzymes, Human Placental Lipids, Human Umbilical Extract, Placental Protein, Hydro
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Glycine Max (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Phytoplacenta Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Verified Jun 2026
Data: CosIng · EWG · CIR