Hydroxyethyl Cyclodextrin
AKA “hydroxyethyl--cyclodextrin, SCHEMBL29401827”
Skin Conditioning
Ingredient Facts
Hydroxyethyl cyclodextrin
AKA: Hydroxyethyl--cyclodextrin, SCHEMBL29401827
Skin Conditioning · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Not Clean
Hydroxyethyl Cyclodextrin is the hydroxyethyl ether of Cyclodextrin
Formula
C38H64O31
Mol. Weight
1016.90
CAS #
-
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A modified cyclodextrin (a sugar-based molecule) developed in the 1980s for pharmaceutical and cosmetic use as a solubilizing and stabilizing agent. Created to improve the delivery and stability of active ingredients in modern formulations.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
Dermal absorption: 2%. Source: CIR Safety Assessment (CIR Seq 680).
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR