Hydroxypalmitoyl Sphinganine
AKA “190249-36-6, Mexanyl GAA, NR33W2353T, Hexadecanamide, 2-hydroxy-N-((1S, 2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl)-, 2-hydroxy-N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, (1S-(1R*, 2S*))-(partial)-, DTXSID90172503, RefChem:789535, DTXCID0094994, HYDROXYPALMITOYL SPHINGANINE [INCI]
Skin Conditioning
Ingredient Facts
Hydroxypalmitoyl sphinganine
AKA: 190249-36-6, Mexanyl GAA, NR33W2353T, Hexadecanamide, 2-hydroxy-N-((1S, 2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl)-, 2-hydroxy-N-(2-hydroxy-1-(hydroxymethyl)heptadecyl)-, (1S-(1R*, 2S*))-(partial)-, DTXSID90172503, RefChem:789535, DTXCID0094994, HYDROXYPALMITOYL SPHINGANINE [INCI]
Skin Conditioning · Hair Conditioning · EWG: 1
Synthetic
Skin Conditioner
Hair Care
Clean
1,3-Dihydroxy-2-amino-[(N-(2-hydroxy)-hexanedecanoyl]-octadecane
Formula
C34H69NO4
Mol. Weight
555.90
CAS #
190249-36-6
Form
Powder
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Developed in the late 20th century as a synthetic ceramide analog designed to mimic natural ceramides found in skin. Created to improve skin barrier function and hydration in modern skincare formulations.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR