Hydroxypropyl Methylcellulose Acetate/Succinate
AKA “Hypromellose acetate succinate, hydroxypropylmethylcellulose acetate succinate, Hypromellose acetate succinate [NF], Hpmcas, Celluloseacetatesuccinate
Ingredient
Ingredient Facts
Hydroxypropyl methylcellulose acetate/succinate
AKA: Hypromellose acetate succinate, Hydroxypropylmethylcellulose acetate succinate, Hypromellose acetate succinate [NF], Hpmcas, Celluloseacetatesuccinate
Ingredient · Film Forming · EWG: 4
Synthetic
Occlusive
Not Clean
Cellulose, 2-hydroxypropyl methyl ether, acetate hydrogen butanedioate
Formula
C10H22O9
Mol. Weight
286.28
CAS #
71138-97-1
Form
Powder
See origin →
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Creates Protective Barrier
Reduces Inflammation
Locks In Moisture
Fights Bacteria
Traditional Use
A chemically modified cellulose derivative developed in the mid-20th century as a specialized film-forming and thickening agent. Used in modern cosmetics for improved texture and stability.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR