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Isobutyl Myristate
AKA “25263-97-2, 2-Methylpropyl tetradecanoate, isobutyl tetradecanoate, Myristic acid, isobutyl ester, Tetradecanoic acid, 2-methylpropyl ester, BT6J85032B, EINECS 246-765-6, NSC-44525, AEC ISOBUTYL MYRISTATE”
Emollient
Ingredient Facts
Isobutyl myristate
AKA: 25263-97-2, 2-Methylpropyl tetradecanoate, Isobutyl tetradecanoate, Myristic acid, Isobutyl ester, Tetradecanoic acid, 2-methylpropyl ester, BT6J85032B, EINECS 246-765-6, NSC-44525, AEC ISOBUTYL MYRISTATE
Emollient · Emollient · EWG: 4
Synthetic
Emollient
Skin Conditioner
Not Clean
Isobutyl myristate
Formula
C18H36O2
Mol. Weight
284.50
CAS #
25263-97-2
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
A synthetic ester synthesized in the early 20th century from isobutanol and myristic acid. Adopted by the cosmetics industry as an emollient and conditioning agent in lotions, creams, and foundations.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Myristic acid reduces skin inflammation and nociception.
Alonso-Castro AJ, Serrano-Vega R, Pérez Gutiérrez S, Isiordia-Espinoza MA, Solorio-Alvarado CR
Journal of food biochemistry, 2022
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Final Report of the Amended Safety Assessment of Myristic Acid and its Salts and Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Isobutyl Myristate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Myristic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Myristic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Myristic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR