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Isocetyl Myristate
AKA “ICM-R, Nikkol ICM-R, 83708-66-1, Myristic acid, isocetyl ester, UNII-69AX3BRR5N, Tetradecanoic acid, 69AX3BRR5N, isohexadecyl ester, RefChem:149150”
Emollient
Ingredient Facts
Isocetyl myristate
AKA: ICM-R, Nikkol ICM-R, 83708-66-1, Myristic acid, Isocetyl ester, UNII-69AX3BRR5N, Tetradecanoic acid, 69AX3BRR5N, Isohexadecyl ester, RefChem:149150
Emollient · Emollient · EWG: 1
Synthetic
Emollient
Skin Conditioner
Clean
Tetradecanoic acid, isohexadecy ester
Formula
C30H60O2
Mol. Weight
452.80
CAS #
83708-66-1
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Modern synthetic ester created to function as an emollient and solvent in cosmetic formulations, designed to improve texture and absorption properties without traditional medicinal or cosmetic applications.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Myristic acid reduces skin inflammation and nociception.
Alonso-Castro AJ, Serrano-Vega R, Pérez Gutiérrez S, Isiordia-Espinoza MA, Solorio-Alvarado CR
Journal of food biochemistry, 2022
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Final Report of the Amended Safety Assessment of Myristic Acid and its Salts and Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Isocetyl Myristate
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Methyl Myristic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Myristic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Isocetyl Myristate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Myristic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR