Isodecyl Salicylate
AKA “85252-25-1, EINECS 286-542-0, Keratoplast, S7097PFP4C, Benzoic acid, 2-hydroxy-, isodecyl ester, EDESAL, DERMOL IDSA, RefChem:791848, DTXSID90234458”
Skin Conditioning
Ingredient Facts
Isodecyl salicylate
AKA: 85252-25-1, EINECS 286-542-0, Keratoplast, S7097PFP4C, Benzoic acid, 2-hydroxy-, Isodecyl ester, EDESAL, DERMOL IDSA, RefChem:791848, DTXSID90234458
Skin Conditioning · Antistatic · EWG: 1
Synthetic
Skin Conditioner
Chemical Exfoliant
Clean
The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Isodecyl Salicylate...
Formula
C17H26O3
Mol. Weight
278.40
CAS #
85252-25-1
Form
Liquid
See origin →
Functions
Antistatic
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Synthetic ester developed in the 20th century as a cosmetic emollient and preservative booster. Combines salicylic acid (historically used for acne and exfoliation) with isodecyl alcohol to create a stable, synthetic ingredient with no traditional use history.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Caution
Benzyl Alcohol, Benzoic Acid, Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.
Corral-Sarasa J, Martínez-Gálvez JM, González-García P, Wendling O, Jiménez-Sánchez L et al.
Cell reports, 2024
4-Hydroxybenzoic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Isodecyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
4-Hydroxybenzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Benzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isodecyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
[Keratoplastic effect of salicyclic acid, sulfur and a tensio-active mixture].
Gloor M, Beier B
Zeitschrift fur Hautkrankheiten, 1984
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR