Isopentyldiol
AKA “3-Methyl-1, 3-butanediol, 3-methylbutane-1, 3-diol, 2568-33-4, 1, 3-Butanediol, 3-methyl-, isoprene glycol, ISOPENTYL DIOL, 3-hydroxy-3-methylbutanol, 19NOL5474Q, 3-methyl-1, 3-butandiol
Ingredient Facts
Isopentyldiol
AKA: 3-Methyl-1, 3-butanediol, 3-methylbutane-1, 3-diol, 2568-33-4, 1, 3-Butanediol, 3-methyl-, Isoprene glycol, ISOPENTYL DIOL, 3-hydroxy-3-methylbutanol, 19NOL5474Q, 3-methyl-1, 3-butandiol
Synthetic · Humectant · EWG: 1
Synthetic
Humectant
Solvent
Clean
Isopentyldiol is a cosmetic ingredient. Also known as 3-Methyl-1. Rated low hazard by EWG.
Formula
C5H12O2
Mol. Weight
104.15
CAS #
50468-22-9, 2568-33-4
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Provides scent
Dissolves other ingredients
Skin Types
all-skin-types
Best For
General
EWG
1
CIR
Insufficient
Pregnancy
CIR Safety Findings
all-shades-safe
Moderate Irritant
Regulatory Status
USAunder review
CANADApermitted
Regulatory Agencies
Addendum to the Final Report on the Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol (JEPT 4(4) 47-61 1980)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report of the Safety Assessment for 2-Bromo-2-Nitropropane-1,3-Diol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Revised Tentative Report: Amended Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
2-Bromo-2-Nitropropane-1,3-Diol
European Commission
EU Cosmetic Ingredient Database (CosIng)
2,3-Butanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Bromo-2-Nitropropane-1,3-Diol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2,3-Butanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isopentyldiol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Bromo-2-nitropropane-1,3-diol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Prospects on bio-based 2,3-butanediol and acetoin production: Recent progress and advances.
Maina S, Prabhu AA, Vivek N, Vlysidis A, Koutinas A et al.
Biotechnology advances, 2022
Kitty Litter Dermatitis from-Bromo-2-Nitropropane-1,3-Diol.
Sullenbarger JW, Hensley B, Travers JB
Skinmed, 2017
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR