Isopropyl Cloprostenate
AKA “Cloprostenol isopropyl ester, Isopropyl cloprostenol, UNII-765298537G, CPG-611295, 5-Heptenoic acid, 5S)-2-((1E, 3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl)-3, 1-methylethyl ester
Synthetic
Ingredient Facts
Isopropyl cloprostenate
AKA: Cloprostenol isopropyl ester, Isopropyl cloprostenol, UNII-765298537G, CPG-611295, 5-Heptenoic acid, 5S)-2-((1E, 3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl)-3, 1-methylethyl ester
Synthetic · Emollient · EWG: 4
Synthetic
Emollient
Skin Conditioner
Hair Care
Synthetic
Clean
Helps condition and soften hair, keeping it smooth and manageable while improving overall texture and shine.
Formula
C25H35ClO6
Mol. Weight
467.00
CAS #
157283-66-4
Form
Oil
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Anti-Inflammatory
Antioxidant
Protects skin from free radical damage caused by UV, pollution, and stress
Improves Elasticity
Softens and detangles hair
Traditional Use
A synthetic analog of the prostaglandin cloprostenol developed for use in eyelash-growth cosmetics. Created to stimulate hair follicle activity and extend the anagen (growth) phase of eyelashes.
Skin Types
all-skin-types
Best For
Loss of Elasticity
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
No
EWG
4
CIR
Insufficient
Pregnancy
No
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR